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Which will be the correct option for the marked place?(a) Acetylcholine(b) Gastrin(c) Histamine(d) Hydrogen ionsI had been asked this question in final exam.Query is from Pharmacotherapy of Peptic Ulcer topic in portion Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Answer»

Right option is (b) Gastrin

For explanation I would SAY: Gastrin secreted by Antral G cell is the hormonal control of acid secretion by parietal cell. Gastrin, Histamine and acetylcholine switch on the PROTON pump thus pumping H+ ions to produce acid in the GASTRIC lumen. Acid in our STOMACH is secreted by the parietal CELLS. Mucous is secreted by the goblet cells.



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