1.

Which will be the correct option for the marked place?(a) Acetylcholine(b) Gastrin(c) Histamine(d) Hydrogen ionsThis question was posed to me in final exam.Question is from Pharmacotherapy of Peptic Ulcer in section Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Answer»

The CORRECT answer is (c) HISTAMINE

Explanation: Cholinergic NEURON secretes ACETYLCHOLINE that bind to the muscarinic receptor in the parietal cell secrete acid into the gastric lumen. Enterochromaffine like cells secrete histamine which again bind to the H2 receptor and through the cAMP pathway helps the parietal cell to secrete acid. Gastrin secreted by ANTRAL G cell is the hormonal control of acid secretion by parietal cell.



Discussion

No Comment Found

Related InterviewSolutions