Which of the following is incorrect about Phred?(a) It is a UNIX program(b) It doesn’t give a probability score in output(c) It is used for base calling(d) It uses a Fourier analysis to resolve fluorescence traces and predict actual peak locations of basesI got this question in an interview for internship.Question is from Genome Sequence Assembly topic in section Genome Mapping, Assembly and Comparison of Bioinformatics

Which of the following is incorrect about Phred?(a) It is a UNIX progr

1.	Which of the following is incorrect about Phred?(a) It is a UNIX program(b) It doesn’t give a probability score in output(c) It is used for base calling(d) It uses a Fourier analysis to resolve fluorescence traces and predict actual peak locations of basesI got this question in an interview for internship.Question is from Genome Sequence Assembly topic in section Genome Mapping, Assembly and Comparison of Bioinformatics
Answer» The correct choice is (b) It doesn’t give a probability score in output The explanation is: It also gives a probability score for each base call that may be ATTRIBUTABLE to error. The commonly accepted score threshold is TWENTY, which corresponds to a 1% chance of error. The HIGHER the score, the better the quality of the sequence reads. If the score VALUE falls below the threshold, human INTERVENTION is required.

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