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Which of the following is not a characteristic of the moieties that are transferred to the substrate in phase II reactions?(a) Simple endogenous molecules are transferred(b) Large molecular sized groups are attached(c) Strong polar groups are attached(d) Strong nonpolar groups are attachedThe question was posed to me by my school teacher while I was bunking the class.The doubt is from Drugs Biotransformation in chapter Biotransformation of Drugs of Drug Biotechnology

Answer»

Correct choice is (d) Strong nonpolar groups are attached

Explanation: The moieties transferred to the SUBSTRATES in a phase II REACTIONS POSSESS characteristics that are, simple endogenous molecules, large groups, and strong polar or IONIC groups are attached to make the substrate water soluble.



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