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Which of the following is not a common N containing functional groups which undergo reduction reactions?(a) Nitro compounds(b) Azo compounds(c) N-oxide compounds(d) Nitrite compoundsI have been asked this question in class test.This is a very interesting question from Drugs Biotransformation topic in portion Biotransformation of Drugs of Drug Biotechnology

Answer»

Correct option is (d) Nitrite compounds

Best explanation: The N-containing FUNCTIONAL groups that commonly undergo bioreduction are NITRO, azo, N-oxide compounds. REDUCTION of the nitro group proceeds via FORMATION of nitroso and hydroxylamine intermediates to YIELD amines.



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