Which of the following is untrue about Gene Order Comparison?(a) When the order of a number of linked genes is conserved between genomes, it is called synteny(b) Generally, gene order is much more conserved compared with gene sequences(c) Generally, gene order is much less conserved compared with gene sequences(d) It is in fact rarely observed among divergent speciesThis question was posed to me during an interview for a job.The above asked question is from Comparative Genomics topic in portion Genome Mapping, Assembly and Comparison of Bioinformatics

Which of the following is untrue about Gene Order Comparison?(a) When

1.	Which of the following is untrue about Gene Order Comparison?(a) When the order of a number of linked genes is conserved between genomes, it is called synteny(b) Generally, gene order is much more conserved compared with gene sequences(c) Generally, gene order is much less conserved compared with gene sequences(d) It is in fact rarely observed among divergent speciesThis question was posed to me during an interview for a job.The above asked question is from Comparative Genomics topic in portion Genome Mapping, Assembly and Comparison of Bioinformatics
Answer» The correct choice is (b) Generally, gene ORDER is much more conserved compared with gene sequences Explanation: Gene order conservation is in FACT rarely OBSERVED among divergent species. Therefore, comparison of syntenic relationships is normally carried out between relatively close LINEAGES. However, if syntenic relationships for certain genes are indeed observed among divergent prokaryotes, they often provide important CLUES to functional relationships of the genes of interest.

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