Which of the following is untrue about Whole Genome Alignment?(a) This helps to reveal the presence of conserved functional elements(b) It doesn’t help to understand sequence conservation between genomes(c) It be accomplished through direct genome comparison or genome alignment(d) The alignment at the genome level is fundamentally no different from the basic sequence alignmentThe question was posed to me during an internship interview.I'd like to ask this question from Comparative Genomics topic in division Genome Mapping, Assembly and Comparison of Bioinformatics

Which of the following is untrue about Whole Genome Alignment?(a) This

1.	Which of the following is untrue about Whole Genome Alignment?(a) This helps to reveal the presence of conserved functional elements(b) It doesn’t help to understand sequence conservation between genomes(c) It be accomplished through direct genome comparison or genome alignment(d) The alignment at the genome level is fundamentally no different from the basic sequence alignmentThe question was posed to me during an internship interview.I'd like to ask this question from Comparative Genomics topic in division Genome Mapping, Assembly and Comparison of Bioinformatics
Answer» Right choice is (b) It doesn’t HELP to understand sequence conservation between genomes The BEST explanation: Regular alignment programs tend to be error prone and inefficient when dealing with long stretches of DNA containing HUNDREDS or THOUSANDS of genes. Another challenge of genome alignment is effective visualization of alignment results. Because it is obviously difficult to sift through and make sense of the extremely large alignments, a graphical representation is a MUST for interpretation of the result.

Discussion

No Comment Found

Related InterviewSolutions

When a sequence is generated from ____ ends of a single clone, the distance between the two opposing fragments of a clone is fixed to ________ meaning that they are always separated by a distance defined by a _____ length (normally 1,000 to 9,000 bases).(a) both, an uncertain range, clone(b) one, an uncertain range, clone(c) both, a certain range, clone(d) both, a certain range, geneThis question was addressed to me in an international level competition.My question is taken from Genome Sequence Assembly topic in division Genome Mapping, Assembly and Comparison of Bioinformatics
Which of the following is incorrect about Phrap?(a) It aligns individual fragments in a pairwise fashion using the Smith–Waterman algorithm(b) It doesn’t take input from Phred(c) It is used for sequence assembly(d) It is a UNIX programThe question was posed to me in homework.This interesting question is from Genome Sequence Assembly in chapter Genome Mapping, Assembly and Comparison of Bioinformatics
The whole genome shotgun approach can produce a draft sequence very rapidly because it is based on the direct sequencing approach.(a) True(b) FalseThe question was asked by my school teacher while I was bunking the class.I'd like to ask this question from Genome Sequencing in portion Genome Mapping, Assembly and Comparison of Bioinformatics
In hierarchical genome sequencing approach, based on the results of _______ mapping _______of the BAC clones on a chromosome can be determined.(a) physical, the locations and orders(b) physical, only the locations(c) cytological, only the locations(d) physical, only the ordersThe question was posed to me by my college professor while I was bunking the class.This intriguing question originated from Genome Sequencing topic in section Genome Mapping, Assembly and Comparison of Bioinformatics
Which of the following is incorrect regarding Automated Genome Annotation?(a) It exists because of the need to develop fast and automated methods to annotate the genomic sequences(b) The automated approach relies on homology detection(c) The automated approach doesn’t rely on heuristic sequence similarity searching(d) Automation brings speed in gene annotation processThe question was asked in a national level competition.This intriguing question comes from Genome Annotation topic in division Genome Mapping, Assembly and Comparison of Bioinformatics
Cytologic maps can be considered to be of _____ resolution and hence somewhat ______ physical maps.(a) very high, inaccurate(b) very low, accurate(c) very high, accurate(d) very low, inaccurateThe question was asked by my college professor while I was bunking the class.This is a very interesting question from Genome Mapping in portion Genome Mapping, Assembly and Comparison of Bioinformatics
Physical maps are constructed by using a chromosome walking technique.(a) True(b) FalseI got this question during a job interview.I'm obligated to ask this question of Genome Mapping in portion Genome Mapping, Assembly and Comparison of Bioinformatics
Which of the following is untrue about Lateral gene transfer?(a) It is also known as vertical gene transfer(b) There is exchange of genetic materials between species(c) It mainly occurs among prokaryotic organisms when foreign genes are acquired through mechanisms(d) It is one of the examples is transformationI got this question during a job interview.My question is taken from Comparative Genomics in chapter Genome Mapping, Assembly and Comparison of Bioinformatics
The remote homology detection helps to shed light on the possible functions of the proteins that previously have no functional information at all.(a) True(b) FalseThis question was posed to me in homework.Question is from Genome Annotation topic in portion Genome Mapping, Assembly and Comparison of Bioinformatics
A minimal constitutes genome, which is a _____ set of genes required for maintaining a free living cellular organism.(a) maximum(b) maximal(c) highest number of set of(d) minimalI had been asked this question in an online quiz.Question is taken from Comparative Genomics in chapter Genome Mapping, Assembly and Comparison of Bioinformatics

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment