Which of the following is untrue regarding Coils?(a) It is a web-based program that detects coiled coil regions in proteins(b) It scans a window of fourteen, twenty-one, or twenty-eight residues(c) It scans a window of fourteen or twenty-one residues only(d) It compares the sequence to a probability matrix compiled from known parallel two-stranded coiled coilsThis question was addressed to me in a national level competition.My question comes from Coiled Coil Prediction topic in section Secondary Structure Prediction of Bioinformatics

Which of the following is untrue regarding Coils?(a) It is a web-based

1.	Which of the following is untrue regarding Coils?(a) It is a web-based program that detects coiled coil regions in proteins(b) It scans a window of fourteen, twenty-one, or twenty-eight residues(c) It scans a window of fourteen or twenty-one residues only(d) It compares the sequence to a probability matrix compiled from known parallel two-stranded coiled coilsThis question was addressed to me in a national level competition.My question comes from Coiled Coil Prediction topic in section Secondary Structure Prediction of Bioinformatics
Answer» CORRECT choice is (c) It scans a window of FOURTEEN or twenty-one residues only Easy explanation: By comparing the similarity scores, the program calculates the probability of the sequence to ADOPT a coiled coil conformation. The program is accurate for solvent-exposed, left-handed coiled COILS, but less sensitive for other types of coiled coil structures, such as buried or right-handed coiled coils.

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