Which of the following is untrue regarding the transmembrane proteins?(a) Constitute up to 30% of all cellular proteins(b) They are responsible for performing a wide variety of important functions in a cell, such as signal transduction, cross-membrane transport, and energy conversion(c) The membrane proteins are also of tremendous biomedical importance(d) They are not drug targets or receptorsI had been asked this question in exam.This interesting question is from Secondary Structure Prediction for Transmembrane Proteins in chapter Secondary Structure Prediction of Bioinformatics

Which of the following is untrue regarding the transmembrane proteins?

1.	Which of the following is untrue regarding the transmembrane proteins?(a) Constitute up to 30% of all cellular proteins(b) They are responsible for performing a wide variety of important functions in a cell, such as signal transduction, cross-membrane transport, and energy conversion(c) The membrane proteins are also of tremendous biomedical importance(d) They are not drug targets or receptorsI had been asked this question in exam.This interesting question is from Secondary Structure Prediction for Transmembrane Proteins in chapter Secondary Structure Prediction of Bioinformatics
Answer» Right choice is (d) They are not DRUG targets or receptors For explanation: The membrane proteins are also of tremendous biomedical importance, as they often SERVE as drug targets for pharmaceutical development. There are two types of integral membrane proteins: α-helical type and β-barrel type. Most transmembrane proteins contain solely α-helices, which are found in the CYTOPLASMIC membrane. A few membrane proteins consist of β-strands FORMING a β- barrel topology, a cylindrical structure composed of ANTIPARALLEL β-sheets.

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