Which of the following statement rightly states “bioactivation”?(a) Formation of high reactive metabolites which interact with tissues to precipitate toxic compounds(b) Formation chelating agents(c) Formation of enzymes which can lyse toxic compounds(d) Stimulating the immune systems to initiate the formation of t cellsI got this question in unit test.The origin of the question is Bioactivation and Tissue Toxicity in division Biotransformation of Drugs of Drug Biotechnology

Which of the following statement rightly states “bioactivation”?(a

1.	Which of the following statement rightly states “bioactivation”?(a) Formation of high reactive metabolites which interact with tissues to precipitate toxic compounds(b) Formation chelating agents(c) Formation of enzymes which can lyse toxic compounds(d) Stimulating the immune systems to initiate the formation of t cellsI got this question in unit test.The origin of the question is Bioactivation and Tissue Toxicity in division Biotransformation of Drugs of Drug Biotechnology
Answer» Correct option is (a) Formation of high REACTIVE metabolites which interact with TISSUES to PRECIPITATE toxic compounds The explanation: Formation of highly reactive metabolites which can interact with the tissues and precipitate out various toxic compounds such as carcinogens, teratogens, etc. is KNOWN as bioactivation or toxicological ACTIVATION.

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