1.

Which xenobiotics yield free radicles on metabolic activation?(a) Thalidomide(b) Aflatoxin(c) Quinones(d) BenzopyreneThe question was posed to me in an interview.This key question is from Bioactivation and Tissue Toxicity in portion Biotransformation of Drugs of Drug Biotechnology

Answer»

Right OPTION is (c) Quinones

To ELABORATE: Quinones, ARYLAMINES, nitroaryls and carbon tetrachloride are some of the EXAMPLES of xenobiotics which yields free radicals. Endogenous compounds such as epinephrine, DOPA can generate free radicals.



Discussion

No Comment Found

Related InterviewSolutions