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You hybridize two cells one of which carries a deletion mutation on chromosome 1. What will you expect to observe?(a) Buckling of chromatin of 1^st cell(b) Buckling of chromatin of 2^nd cell(c) Twisting and loop formation between the two chromatins(d) No observable differenceThe question was asked in class test.Question is from Chromosomal Abnormalities : Deletion in division Chromosomal Basis of Inheritance of Cytogenetics

Answer»

Right OPTION is (b) Buckling of chromatin of 2^nd cell

Easiest explanation: As chromosome 1 of 1^st cell carries the deletion it will have less genes than that of the counterpart on the 2^nd cell. There will be an ERROR in a pairing where the EXTRA part of 2^nd cell chromatin CORRESPONDING to the deleted gene will buckle.



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