A frame shift mutation will have minimum effect when it leads to ______________(a) Insertion of 2 bases(b) Deletion of 1 base(c) Insertion of 3 bases(d) Deletion of 2 basesThe question was asked during an online exam.The doubt is from DNA Mutation in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

A frame shift mutation will have minimum effect when it leads to _____

1.	A frame shift mutation will have minimum effect when it leads to ______________(a) Insertion of 2 bases(b) Deletion of 1 base(c) Insertion of 3 bases(d) Deletion of 2 basesThe question was asked during an online exam.The doubt is from DNA Mutation in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics
Answer» Right answer is (c) Insertion of 3 bases For explanation: Frame shift mutations lead to lease effect when they lead to an insertion or deletion of 3 bases, as due to our CODON being triplet this doesn’t shift the reading frame. However, if the codon THUS lost or added is a very important ONE in the gene, there could be SERIOUS consequences.

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