Absence of the intermediate filament desmin, has a negative impact on _______________(a) hepatocytes(b) nerve cells(c) epithelial cells(d) muscle cellsI have been asked this question during an interview for a job.The above asked question is from Cytoskeleton in section Cytoskeleton and Cell Motility of Cell Biology

Absence of the intermediate filament desmin, has a negative impact on

1.	Absence of the intermediate filament desmin, has a negative impact on _______________(a) hepatocytes(b) nerve cells(c) epithelial cells(d) muscle cellsI have been asked this question during an interview for a job.The above asked question is from Cytoskeleton in section Cytoskeleton and Cell Motility of Cell Biology
Answer» The correct answer is (d) muscle CELLS To elaborate: Absence of intermediate FILAMENTS desmins makes the muscle cells extremely fragile. Desmin polypeptide plays a key ROLE in maintaining the ALIGNMENT of MYOFIBRILS of the muscle cells.

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