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Accurate models applicable to a range of process conditions are not rare.(a) True(b) FalseI had been asked this question in an interview for internship.My question is based upon Monitoring and Control of Bioreactors topic in chapter Reactor Engineering of Bioprocess Engineering

Answer»

Correct choice is (b) False

To EXPLAIN I would say: Development of a comprehensive model covering all key aspects of a particular bioprocess and able to predict the effects of a wide range of culture variables is a DEMANDING exercise. Accurate models applicable to a range of process conditions are rare. As many aspects of fermentation are poorly under- stood, it difficult to devise mathematical models covering these areas. For EXAMPLE, the response of cells to spatial variations in dissolved-oxygen and substrate levels in fermenters, or the effect of impeller design on microbial growth and productivity, is not generally INCORPORATED into models because the SUBJECT has been inadequately studied.



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