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Aggregation of neurofilaments leads to ____________(a) vision disorders(b) skin disorders(c) lung disorders(d) neurodegenerative disordersThe question was posed to me in a national level competition.My doubt is from Cytoskeleton in chapter Cytoskeleton and Cell Motility of Cell Biology

Answer»

Correct choice is (d) neurodegenerative disorders

Easiest explanation: Neurofilaments are the intermediate FILAMENTS that CONSTITUTE mature neuronal cells. AGGREGATION of these neurofilaments blocks AXONAL transport, associated with neurodegenerative disorders like Alzheimer’s and Parkinson’s disease.



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