BLAST uses a _______ to find matching words, whereas FASTA identifies identical matching words using the _____(a) substitution matrix, hashing procedure(b) substitution matrix, blocks(c) hashing procedure, substitution matrix(d) ktups, substitution matrixThis question was addressed to me in a national level competition.The query is from Comparison of FASTA and BLAST in section Database Similarity Searching of Bioinformatics

BLAST uses a _______ to find matching words, whereas FASTA identifies

1.	BLAST uses a _______ to find matching words, whereas FASTA identifies identical matching words using the _____(a) substitution matrix, hashing procedure(b) substitution matrix, blocks(c) hashing procedure, substitution matrix(d) ktups, substitution matrixThis question was addressed to me in a national level competition.The query is from Comparison of FASTA and BLAST in section Database Similarity Searching of Bioinformatics
Answer» The CORRECT choice is (a) substitution matrix, HASHING procedure Easy explanation: BLAST and FASTA have been shown to perform almost equally well in regular DATABASE searching; However, there are some NOTABLE differences between the two approaches. The major difference is in the seeding step– BLAST uses a substitution matrix to find matching words, whereas FASTA identifies identical matching words using the hashing procedure.

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