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Score can be negative in Smith–Waterman algorithm.(a) True(b) FalseThe question was asked during an internship interview.I'd like to ask this question from Database Searching with the Smith in portion Database Similarity Searching of Bioinformatics

Answer»

The CORRECT answer is (B) False

To explain: Negative score is SET to 0. In Needleman–Wunsch ALGORITHM, the Score can be negative. ALSO, in Smith–Waterman algorithm, in tracing back step, it begins with the highest score, ends when 0 is encountered.



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