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Calico cats are always______________(a) Male(b) Female(c) Klinefelter(d) TurnerI got this question in an online quiz.This intriguing question comes from Dosage Compensation Mechanism for X linked Genes topic in chapter Chromosomes and Sex Determination of Cytogenetics

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Right option is (b) Female

To elaborate: In CALICO cats there is development of black and orange and white patches. This is POSSIBLE only when the dominant O allele is turned off in some X chromosome DUE to DOSAGE compensation. As males have only one X chromosome they are never turned off. THUS, only females show this trait.



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