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Class-switching of antibodies can occur by changing the ___________________(a) heavy chain(b) light chain(c) pH(d) temperatureThis question was addressed to me by my college director while I was bunking the class.My question is from Molecular Basis of Immunity topic in chapter Immune Response of Cell Biology

Answer»

The correct option is (a) HEAVY chain

Easy explanation: The class-switching of antibodies can TAKE place by CHANGING the heavy chains of immunoglobulins without make any CHANGE to the antigen binding region. B cells can change the antibodies they make even after PRODUCING them.



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