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DNA sequences are sometimes more biased than protein sequences because of preferential codon usage in different organisms.(a) True(b) FalseThis question was addressed to me by my college director while I was bunking the class.Question is taken from Forms of Tree Representation in chapter Molecular Phylogenetics of Bioinformatics

Answer»

Right answer is (a) True

Easiest explanation: In this case, different codons for the same amino acid are USED at different frequencies, LEADING to sequence variations not attributable to evolution. In addition, the genetic code of mitochondria varies from the STANDARD genetic code. Therefore, for comparison of mitochondria protein-coding genes, it is necessary to translate the DNA SEQUENCES into protein sequences.



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