During pregnancy, drug distribution is more. Which of the following sentences describe the given fact better?(a) The baby needs more drug(b) The mother needs more drug due to high metabolism(c) The surface area increases in the mother’s body due to the presence of uterus, placenta, and foetus. Thus more area for distribution of drugs(d) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get distributedThis question was addressed to me at a job interview.This is a very interesting question from Drug Distribution topic in portion Distribution of Drugs of Drug Biotechnology

During pregnancy, drug distribution is more. Which of the following se

1.	During pregnancy, drug distribution is more. Which of the following sentences describe the given fact better?(a) The baby needs more drug(b) The mother needs more drug due to high metabolism(c) The surface area increases in the mother’s body due to the presence of uterus, placenta, and foetus. Thus more area for distribution of drugs(d) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get distributedThis question was addressed to me at a job interview.This is a very interesting question from Drug Distribution topic in portion Distribution of Drugs of Drug Biotechnology
Answer» The correct choice is (d) The growth of the uterus, PLACENTA, and foetus increases the volume thus INCREASING DISTRIBUTION. And EVEN the BABY forms a separate compartment for a drug to get distributed Explanation: Pregnancy leads to the growth of uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for the drug to get distributed. The plasma and the ECF volume also increase.

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