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Which cell make up the blood-brain barrier?(a) Squamous epithelium cells(b) Fat cells(c) Red blood cell(d) Endothelial cellsI have been asked this question in a job interview.My query is from Drug Distribution topic in section Distribution of Drugs of Drug Biotechnology

Answer»

Correct OPTION is (d) Endothelial CELLS

Easiest explanation: The brain capillaries are made up of EPITHELIAL cells joined to one another by continuous tight intercellular junctions thereby MAKING the blood-brain barrier. These are highly SPECIALIZED capillaries which are much less permeable to water-soluble drugs.



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