Etoposide and doxorubicin, the drugs used in Cancer treatment target the enzyme ___________(a) topoisomerase I(b) topoisomerase II(c) helicase(d) isomeraseThe question was posed to me during an online exam.This is a very interesting question from Genome Structure topic in portion Nature of Genome of Cell Biology

Etoposide and doxorubicin, the drugs used in Cancer treatment target t

1.	Etoposide and doxorubicin, the drugs used in Cancer treatment target the enzyme ___________(a) topoisomerase I(b) topoisomerase II(c) helicase(d) isomeraseThe question was posed to me during an online exam.This is a very interesting question from Genome Structure topic in portion Nature of Genome of Cell Biology
Answer» Right option is (b) topoisomerase II Easy EXPLANATION: Both these drugs are TARGET DNA in Cancer cells. They bind to topoisomerase II enzyme which prevents the DNA STANDS from re-ligating and THUS causes it to BREAK.

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