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How can you determine the extracellular fluid volume?(a) Evans blue(b) Na+(c) D20(d) Tritiated waterThis question was addressed to me during an online interview.This intriguing question comes from Drugs Distribution in chapter Distribution of Drugs of Drug Biotechnology |
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Answer» CORRECT option is (B) Na+ Easy explanation: ECF volume can be determined by substances which can easily penetrate the CAPILLARY membrane and distribute to the whole ECF but will not cross the membrane for e.g. Na+, Cl^–, Br^–, SCN^–, SO4^2-. |
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