In addition to amyloid-β peptide, which other protein is misfolded in the brains of Alzheimer’s disease patients?(a) Alpha(b) Zau(c) Theta(d) TauI have been asked this question by my school principal while I was bunking the class.My doubt stems from Chemical Basis of Life in portion Chemical Basis of Life of Cell Biology

In addition to amyloid-β peptide, which other protein is misfolded in

1.	In addition to amyloid-β peptide, which other protein is misfolded in the brains of Alzheimer’s disease patients?(a) Alpha(b) Zau(c) Theta(d) TauI have been asked this question by my school principal while I was bunking the class.My doubt stems from Chemical Basis of Life in portion Chemical Basis of Life of Cell Biology
Answer» The correct choice is (d) Tau To EXPLAIN I would say: The tau-protein FUNCTIONS as a part of nerve CELL’s cytoskeleton. In PATIENTS with Alzheimer’s this protein develops into bundles of tangle cellular FILAMENTS called neurofibrillary tangles (or NFTs) as a result of misfolding.

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