In an experiment to check mutagenicity of a substance, we feed the mutagen to a rat and then use the rat _______ extract within the media. This ensures_____________(a) Kidney; the mutagen can be at a higher concentration(b) Liver; the media has adequate iron from rat RBC(c) Liver; the mutagen is processed(d) Kidney; the mutagen is broken downThe question was posed to me in semester exam.Question is from DNA Mutation in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

In an experiment to check mutagenicity of a substance, we feed the mut

1.	In an experiment to check mutagenicity of a substance, we feed the mutagen to a rat and then use the rat _______ extract within the media. This ensures_____________(a) Kidney; the mutagen can be at a higher concentration(b) Liver; the media has adequate iron from rat RBC(c) Liver; the mutagen is processed(d) Kidney; the mutagen is broken downThe question was posed to me in semester exam.Question is from DNA Mutation in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics
Answer» Right choice is (C) Liver; the mutagen is processed Best explanation: Rat is a mammal similar to human being. In us the food undergoes several processing steps than it would in CASE of a simple prokaryote LIKE bacteria. Thus, using a rat liver extract ENSURES that the functional state of the substance is in the extract ensuring more efficiency. Liver processed all the toxins so its extract is used.

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