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In Smith–Waterman algorithm, in initialization Step, the _________ row and ________ column are subject to gap penalty.(a) first, first(b) first, second(c) second, First(d) first, lastI have been asked this question in semester exam.My query is from Database Searching with the Smith topic in section Database Similarity Searching of Bioinformatics

Answer»

The CORRECT answer is (a) first, first

The explanation: In Smith–Waterman ALGORITHM, first ROW and first column are set to 0. In the Needleman Wunsch algorithm, First row and first column are subject to gap PENALTY.



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