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Maximum rate of oxygen transfer occurs when?(a) CAL = 0(b) CAL < 0(c) CAL >= 1(d) CAL > 1This question was posed to me in class test.I would like to ask this question from Oxygen Uptake in Cell Cultures topic in portion Mass Transfer of Bioprocess Engineering

Answer»

The correct option is (a) CAL = 0

Easiest explanation: First, let us estimate the maximum CELL CONCENTRATION that can be supported by the fermenter’s oxygen-transfer system. For a GIVEN set of operating conditions, the maximum rate of oxygen transfer occurs when the concentration-difference DRIVING force (C*AL – CAL) is highest, i.e. when the concentration of DISSOLVED oxygen CAL is zero.



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