Neurofibrillary tangles, found in the brain cells of persons with neurodegenerative disorders consists of _______________(a) intermediate filaments(b) microtubule-associated proteins(c) microtubules(d) phospholipidsI had been asked this question during an internship interview.Question is taken from Cytoskeleton topic in division Cytoskeleton and Cell Motility of Cell Biology

Neurofibrillary tangles, found in the brain cells of persons with neur

1.	Neurofibrillary tangles, found in the brain cells of persons with neurodegenerative disorders consists of _______________(a) intermediate filaments(b) microtubule-associated proteins(c) microtubules(d) phospholipidsI had been asked this question during an internship interview.Question is taken from Cytoskeleton topic in division Cytoskeleton and Cell Motility of Cell Biology
Answer» Correct choice is (b) microtubule-associated proteins For explanation I would SAY: Neurofibrillary TANGLES found in the brain CELLS of neurodegenerative diseases’ patients consists of tangled filaments of EXCESSIVELY phosphorylated ‘tau’ molecules. Tau molecules are a TYPE of MAPs (microtubule-associated proteins).

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