Proteins can interact with a DNA molecule by ____________________(a) fitting into the grooves(b) interacting with the base pairs(c) hydrophilic interactions(d) covalent linkagesThis question was posed to me in an international level competition.My question is taken from Gene Chemical Nature in section Nature of Genome of Cell Biology

Proteins can interact with a DNA molecule by ____________________(a) f

1.	Proteins can interact with a DNA molecule by ____________________(a) fitting into the grooves(b) interacting with the base pairs(c) hydrophilic interactions(d) covalent linkagesThis question was posed to me in an international level competition.My question is taken from Gene Chemical Nature in section Nature of Genome of Cell Biology
Answer» The correct choice is (a) fitting into the grooves The explanation is: Proteins have domains that FIT into major and minor grooves of the DNA molecule. A PROTEIN interacting with the DNA in this way can read the SEQUENCE of NUCLEOTIDES without having to separate the strands.

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