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Shine-Dalgarno sequence is present in the ____________________(a) hnRNA(b) mRNA(c) tRNA(d) siRNAThis question was posed to me by my college professor while I was bunking the class.The doubt is from Gene Expression in section Gene Expression of Cell Biology

Answer»

The correct choice is (b) mRNA

To elaborate: The Shine-Dalgarno sequence is present 5-10 NUCLEOTIDES upstream of the initiation CODON in the bacterial mRNA. The 16S ribosomal RNA has a COMPLEMENTARY sequence for it which leads to the binding of 30S SMALL ribosomal SUBUNIT on the mRNA strand.



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