The concept of “induced fit” refers to the fact that _______(a) When a substrate binds to an enzyme, the enzyme induces a loss of water (desolvation) from the substrate(b) Substrate binding may induce a conformational change in the enzyme, which then brings catalytic groups into proper orientation(c) Enzyme-substrate binding induces an increase in the reaction entropy, thereby catalyzing the reaction(d) Enzyme specificity is induced by enzyme-substrate bindingThis question was addressed to me in an interview for internship.This is a very interesting question from Determining Enzyme Kinetic Constants from Batch Data topic in portion Homogenous Reactions of Bioprocess Engineering

The concept of “induced fit” refers to the fact that _______(a) Wh

1.	The concept of “induced fit” refers to the fact that _______(a) When a substrate binds to an enzyme, the enzyme induces a loss of water (desolvation) from the substrate(b) Substrate binding may induce a conformational change in the enzyme, which then brings catalytic groups into proper orientation(c) Enzyme-substrate binding induces an increase in the reaction entropy, thereby catalyzing the reaction(d) Enzyme specificity is induced by enzyme-substrate bindingThis question was addressed to me in an interview for internship.This is a very interesting question from Determining Enzyme Kinetic Constants from Batch Data topic in portion Homogenous Reactions of Bioprocess Engineering
Answer» Correct answer is (b) SUBSTRATE binding may induce a conformational change in the enzyme, which then BRINGS catalytic groups into proper orientation Explanation: Induced-fit MODEL A proposed mechanism of interaction between an enzyme and a substrate. It postulates that exposure of an enzyme to a substrate CAUSES the active site of the enzyme to change shape in order to allow the enzyme and substrate to BIND.

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