“The kLa value will depend upon the design and operating conditions of the fermenter”, is this statement true or false?(a) True(b) FalseI had been asked this question in an online interview.The query is from Measurement of KLa topic in section Mass Transfer of Bioprocess Engineering

“The kLa value will depend upon the design and operating conditions

1.	“The kLa value will depend upon the design and operating conditions of the fermenter”, is this statement true or false?(a) True(b) FalseI had been asked this question in an online interview.The query is from Measurement of KLa topic in section Mass Transfer of Bioprocess Engineering
Answer» Right choice is (a) True The best I can explain: The value of kLa is unique to both the size and configuration of a reactor vessel. Although some empirically derived expressions have been PUBLISHED for predicting kLa VALUES in non-Newtonian fluids, there is no agreed upon set of equations that account for all of the variables that can affect the results. Accordingly, predicting kLa is not possible, and kLa studies NEED to be performed for bioreactors individually. The kLa value will depend upon the design and operating conditions of the fermenter and will be affected by the variables such as – AERATION rate, – agitation rate and – impeller design.

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