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The main application of pairwise alignment is retrieving biological sequences in databases based on similarity.(a) True(b) FalseThe question was asked in a national level competition.My doubt stems from Heuristic Database Searching in chapter Database Similarity Searching of Bioinformatics

Answer»

Correct option is (a) True

Easiest EXPLANATION: This process involves submission of a query SEQUENCE and PERFORMING a pairwise comparison of the query sequence with all individual sequences in a database. THUS, database similarity searching is pairwise alignment on a large scale. This type of searching is one of the most effective ways to assign putative functions to newly DETERMINED sequences.



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