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The Wiskott-Aldrich syndrome is caused due the lack of functional ____________ protein.(a) ActA(b) Arf1(c) WASP(d) WAVEThis question was posed to me in an interview for job.This is a very interesting question from Non-muscle Motility in chapter Cytoskeleton and Cell Motility of Cell Biology |
Answer» CORRECT OPTION is (c) WASP To explain I would say: Mammalian cells have a family of proteins (WASP/WAVE family) that activates Arp 2/3 complex at the site of stimulation near the plasma MEMBRANE. Patients of Wiscott-Aldris syndrome LACK the functional WASP protein in their white blood cells. |
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