To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?(a) 1080 ml(b) 1080 g(c) 1080 mg(d) 1g/mlThe question was posed to me by my school teacher while I was bunking the class.Asked question is from One & Two Compartment Open Model topic in division Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

To have a plasma distribution value of 900 ml and plasma drug concentr

1.	To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?(a) 1080 ml(b) 1080 g(c) 1080 mg(d) 1g/mlThe question was posed to me by my school teacher while I was bunking the class.Asked question is from One & Two Compartment Open Model topic in division Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology
Answer» Correct answer is (C) 1080 mg Easy explanation: The apparent VOLUME of distribution VD is given by Amount of drug in the body (X) / plasma drug CONCENTRATION (C). Vd is expressed in liters or ml. to find out the amount of drug, the EQUATION is the apparent volume of distribution (Vd)*plasma drug concentration (C).

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