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What are kuffer cells?

Answer» Kupffer cells are the specialized macrophages located in the liver, particularly at the lining of liver sinusoids. They are part of the mononuclear phagocyte system. Their name is derived from Karl Wilhelm von Kupffer, a German anatomist who was the first to describe them in 1876. The Kupffer cells originate from bone marrow stem cells and migrate to the liver via the bloodstream as monocytes.


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