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What competes with substrate for active site?(a) Competitive inhibition(b) Uncompetitive inhibition(c) Non-competitive inhibition(d) Pure Non-competitive inhibitionThis question was posed to me during a job interview.Question is taken from Determining Enzyme Kinetic Constants from Batch Data in chapter Homogenous Reactions of Bioprocess Engineering

Answer»

The correct answer is (a) Competitive inhibition

The best I can explain: When a fake SUBSTRATE BINDS to the active site of an enzyme, it can’t be processed in the same WAY and it won’t turn into a product. A fake substrate is called a competitive inhibitor. Competitive inhibitors bind the active site of an enzyme, preventing a real substrate from binding and a product from being FORMED.



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