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What drives the conformational change in the ribosome?(a) GTP hydrolysis(b) AMP hydrolysis(c) ATP hydrolysis(d) GDP hydrolysisI got this question in an online interview.Origin of the question is Gene Expression topic in chapter Gene Expression of Cell Biology

Answer»

The correct answer is (a) GTP hydrolysis

For EXPLANATION I would say: The large RIBOSOMAL subunit joins the mRNA strand when initiator TRNA is bound and IF3 is DISPLACED. After a large subunit joins the complex, GTP is hydrolyzed to drive the conformational change in the ribosome so as to release IF2.



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