What happens when an obese person is given with a lipophilic drug?(a) Drug aggregation will begin(b) He cannot absorb lipophilic drugs(c) High adipose tissue take up most of the lipophilic drug(d) A large amount of drug is needed as the person’s weight is moreI got this question in my homework.Question is taken from Drug Distribution in portion Distribution of Drugs of Drug Biotechnology

What happens when an obese person is given with a lipophilic drug?(a)

1.	What happens when an obese person is given with a lipophilic drug?(a) Drug aggregation will begin(b) He cannot absorb lipophilic drugs(c) High adipose tissue take up most of the lipophilic drug(d) A large amount of drug is needed as the person’s weight is moreI got this question in my homework.Question is taken from Drug Distribution in portion Distribution of Drugs of Drug Biotechnology
Answer» Right OPTION is (c) High adipose tissue take up most of the lipophilic drug For explanation I would say: The high adipose tissue in the obese person take up a large FRACTION of the lipophilic drugs. THOUGH the perfusion through it is low. The high fatty acid levels in obese person ALTER the binding characteristics of acidic drugs.

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