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What is the equation for bioavailability?(a) [AUC]std Dstd τtest / [AUC]test Dtest τstd(b) [AUC]test Dtest τstd / [AUC]std Dstd τtest(c) [AUC]test Dstd τtest / [AUC]std Dtest τstd(d) 1 / [AUC]std Dtest τstdThis question was posed to me by my college director while I was bunking the class.My question is based upon Bioavailability topic in section Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer»

Correct answer is (c) [AUC]TEST Dstd τtest / [AUC]std Dtest τstd

To EXPLAIN I would say: The equation of bioavailability is [AUC]test Dstd τtest / [AUC]std Dtest τstd, D stands for dose ADMINISTERED, test and std indicate the test and standard DOSES of the same drug to determine the relative availability. The dosing INTERVAL is τ.



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