What is the function of the blood-testis barrier?(a) Restricts the passage of drug to the testis(b) Restricts the passage of drug to sperms(c) Restricts the passage of drugs to spermatocytes(d) Restricts the passage of drugs to spermatocytes and spermatidsI got this question in semester exam.My question is based upon Drug Distribution in section Distribution of Drugs of Drug Biotechnology

What is the function of the blood-testis barrier?(a) Restricts the pas

1.	What is the function of the blood-testis barrier?(a) Restricts the passage of drug to the testis(b) Restricts the passage of drug to sperms(c) Restricts the passage of drugs to spermatocytes(d) Restricts the passage of drugs to spermatocytes and spermatidsI got this question in semester exam.My question is based upon Drug Distribution in section Distribution of Drugs of Drug Biotechnology
Answer» The correct choice is (d) Restricts the passage of DRUGS to SPERMATOCYTES and spermatids For explanation I would say: Blood-TESTIS barrier is a tight JUNCTION between Sertoli CELLS located at the capillary endothelial level of the testis. It acts as the blood-testes barrier restricting drugs to spermatocytes and spermatids.

Discussion

No Comment Found

Related InterviewSolutions

How a patient’s plasma volume can be determined?(a) Evans blue(b) Na+(c) D20(d) Tritiated waterI have been asked this question in my homework.My question comes from Drugs Distribution topic in chapter Distribution of Drugs of Drug Biotechnology
In equation X=Vd C, what does Vd denotes?(a) Density(b) Volume of blood(c) Volume of body(d) The volume of the body fluid in which the drug is getting dissolvedI got this question during an interview.This intriguing question originated from Drugs Distribution topic in chapter Distribution of Drugs of Drug Biotechnology
The extent to which a drug is distributed is a tissue depends upon ___________ and _____________(a) The concentration of a drug, tissue/blood partition coefficient of drug(b) Tissue volume, tissue/blood partition coefficient of drug(c) Tissue surface area, tissue/blood partition coefficient of drug(d) Blood density upon the tissue, tissue/blood partition coefficient of drugI have been asked this question during an online interview.I'd like to ask this question from Drug Distribution topic in section Distribution of Drugs of Drug Biotechnology
Placental barrier is more effective than the Blood-Brain Barrier.(a) True(b) FalseI got this question during an interview for a job.This intriguing question originated from Drug Distribution topic in division Distribution of Drugs of Drug Biotechnology
Which one of the following sentences will be the actual definition of distribution?(a) Transfer of drug from the administration dosage to surrounding fluid(b) Transfer of drug from the surrounding the fluid to the blood(c) Transfer of the drug from the oral cavity to the intestine(d) Reversible transfer of drug between blood and extravascular fluids and tissuesThis question was addressed to me in an interview.The doubt is from Drug Distribution in portion Distribution of Drugs of Drug Biotechnology
Why dopamine cannot be administered for the disease Parkinsonism?(a) Don’t have a medicine(b) It is not the medicine(c) Cannot cross the blood-brain barrier(d) Forms aggregate and thus cannot cross the BBBThe question was posed to me at a job interview.My question comes from Drug Distribution topic in portion Distribution of Drugs of Drug Biotechnology
How will you determine the intracellular fluid volume?(a) Evans blue(b) Na+(c) Difference between total body water and ECF volume(d) Tritiated waterI had been asked this question in my homework.I'm obligated to ask this question of Drugs Distribution in division Distribution of Drugs of Drug Biotechnology
Disease state of a patient can influence drug distribution across the body.(a) True(b) FalseI had been asked this question in exam.The above asked question is from Drug Distribution topic in chapter Distribution of Drugs of Drug Biotechnology
Which cell make up the blood-brain barrier?(a) Squamous epithelium cells(b) Fat cells(c) Red blood cell(d) Endothelial cellsI have been asked this question in a job interview.My query is from Drug Distribution topic in section Distribution of Drugs of Drug Biotechnology
Which of the following drug cannot pass through the plasma membrane barrier?(a) Drug size less than 50 Dalton(b) Lipophilic drugs 50-600 Dalton(c) Polar or ionized drugs of size greater than 50 Dalton(d) Drug size more than 600 DaltonThe question was asked in examination.Query is from Drug Distribution topic in chapter Distribution of Drugs of Drug Biotechnology

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment