1.

What takes place when siRNAs are used in place of dsRNA in mammalian cells?(a) gene knock-down(b) apoptosis(c) necrosis(d) aggregationI got this question by my college professor while I was bunking the class.The question is from Gene Expression topic in section Gene Expression of Cell Biology

Answer»

Correct choice is (a) gene knock-down

Explanation: When small interfering RNA are used in place of double STRANDED RNA, gene knock-down takes place. Subsequently there is INHIBITION of specific protein SYNTHESIS encoded by an mRNA having the same nucleotide sequence as that of INJECTED siRNA.



Discussion

No Comment Found

Related InterviewSolutions