Which equation plot is being shown in the picture?(a) Michaelis-Menten plot(b) One compartment characteristics graph(c) Two compartment characteristics graph(d) Two compartment administered extravascularly characteristics plotThe question was posed to me in examination.I would like to ask this question from Non Linearity of Drugs topic in section Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Which equation plot is being shown in the picture?(a) Michaelis-Menten

1.	Which equation plot is being shown in the picture?(a) Michaelis-Menten plot(b) One compartment characteristics graph(c) Two compartment characteristics graph(d) Two compartment administered extravascularly characteristics plotThe question was posed to me in examination.I would like to ask this question from Non Linearity of Drugs topic in section Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology
Answer» Correct answer is (a) Michaelis-Menten plot To explain: The plot is of Michaelis-Menten EQUATION –dC/dt = Vmax C/Km+C, Initially the rate increases linearly with concentration thus SHOWING first order kinetics. It becomes MIXED order at HIGHER concentration and then reaches maximum Vmax. Beyond this, it proceeds at a constant rate.

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