Which genetic disorder is associated with dysfunction of gap junction?(a) Vohwinkel’s syndrome(b) Down’s syndrome(c) Zellweger Syndrome(d) Bubble Boy SyndromeThe question was asked in exam.My question is from Extracellular Matrix and Cell Interactions topic in portion Extracellular Matrix and Cell Interactions of Cell Biology

Which genetic disorder is associated with dysfunction of gap junction?

1.	Which genetic disorder is associated with dysfunction of gap junction?(a) Vohwinkel’s syndrome(b) Down’s syndrome(c) Zellweger Syndrome(d) Bubble Boy SyndromeThe question was asked in exam.My question is from Extracellular Matrix and Cell Interactions topic in portion Extracellular Matrix and Cell Interactions of Cell Biology
Answer» Correct ANSWER is (a) Vohwinkel’s syndrome The BEST I can explain: Vohwinkel’s syndrome is a skin disease caused by a disorder in the gap junction. It is characterized by THICK calluses in the PALMS of hands and foot. This disease is seen in the infant STAGES or early childhood.

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