Which of the following agents can lead to both addition and deletion mutation?(a) UV(b) 5 Bromo Uracil(c) Proflavin(d) HydroxylationI had been asked this question in examination.This intriguing question comes from DNA Mutation topic in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Which of the following agents can lead to both addition and deletion m

1.	Which of the following agents can lead to both addition and deletion mutation?(a) UV(b) 5 Bromo Uracil(c) Proflavin(d) HydroxylationI had been asked this question in examination.This intriguing question comes from DNA Mutation topic in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics
Answer» The correct answer is (C) PROFLAVIN Explanation: Proflavin, like Ethidium bromide is an intercalating agent. This when inserted in DNA can LEAD to addition of a random base, and when lost can lead to DELETION.

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