Which of the following is a result of a sense mutation?(a) Sickle cell anemia(b) Thalassemia(c) Mutation in beta globin leading to abnormal clotting and bleeding(d) Down’s syndromeI got this question in an online quiz.The question is from DNA Mutation topic in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Which of the following is a result of a sense mutation?(a) Sickle cell

1.	Which of the following is a result of a sense mutation?(a) Sickle cell anemia(b) Thalassemia(c) Mutation in beta globin leading to abnormal clotting and bleeding(d) Down’s syndromeI got this question in an online quiz.The question is from DNA Mutation topic in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics
Answer» The correct answer is (b) Thalassemia Explanation: In Thalassemia the alpha globin is 141 amino ACIDS long as the UAA codon is changed to CAA, i.e a stop codon is changed to a glutamic acid. While sickle CELL anemia is due to a mis sense MUTATION and c is due to a nonsense mutation and d due to trisomy.

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