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Which of the following is incorrect regarding CONPRO?(a) It is a web-based program that uses a consensus method(b) It is used to identify promoter elements for human DNA(c) cDNA does not play a role in prediction(d) The program uses the information to search the human genome database for the position of the geneI got this question in an online quiz.My enquiry is from Prediction Algorithms in section Promoter and Regulatory Element Prediction of Bioinformatics

Answer»

Right option is (c) cDNA does not PLAY a role in prediction

For explanation: To use the PROGRAM, a user supplies the TRANSCRIPT sequence of a gene (cDNA). It then uses the GENSCAN program to predict 5’ untranslated exons in the UPSTREAM region. Once the 5’-most exon is located, a further upstream region (1.5 kb) is used for promoter prediction, which relies on a combination of five promoter prediction programs, TSSG, TSSW, NNPP, PROSCAN, and PromFD.



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