Which of the following is not an important parameter of plasma level time studies?(a) Cmax(b) Tax(c) The area under the plasma level-time curve(d) Steady state levelThis question was addressed to me in quiz.I would like to ask this question from Bioavailability topic in chapter Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Which of the following is not an important parameter of plasma level t

1.	Which of the following is not an important parameter of plasma level time studies?(a) Cmax(b) Tax(c) The area under the plasma level-time curve(d) Steady state levelThis question was addressed to me in quiz.I would like to ask this question from Bioavailability topic in chapter Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology
Answer» The CORRECT option is (d) Steady state level Easiest explanation: Cmax is the peak plasma concentration which shows WHETHER the drug is being absorbed systemically so that it can be able to provide a therapeutic response. Tmax is the peak time which will give the indication of the RATE of ABSORPTION. The AREA under the plasma level-time curve gives the measure of the quantity of absorption of the drug that reaches the systemic circulation.

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